Ayurveda Treatment Methods

A Guide Line To Ayurveda Treatments & Principles

 DRUG INTERACTIONS BETWEEN AYURVEDIC AND ALLOPATHIC (Modern) MEDICINES

 

 

 Use of Ayurvedic drugs and allopathic medications simultaneously has led to potential chances for interactions between the drugs of two systems.

In this article I am discussing that type of drug integrations.

Recently I notice a news that problem in  INR of a patient using ecosprin, detailed investigation revealed that he used Triphala churna (Ayurveda drug) for constipation. When triphala churna stopped ;  he became stable.

I am mentioning other ayurvedic drugs for the safety purpose   

 

  • Interation of Turmeric  ( Haridra - Curcuma longa ) and warfarin.

 

The Centre for Adverse Reaction Monitoring (CARM) recently received a case report describing a patient taking warfarin who began taking a turmeric containing product. The patient had stable INR measurements, but within a few weeks of commencing turmeric their INR increased to over 10. There is a risk of serious bleeding when the INR gets this high.

  • DEVADARVYARISHTAM
  • DEVADARVYARISHTAM
  • PIPPALYASAVAM
  • NIMBAHARIDRADI CHURNAM
  • MAHAKALYANAKAGHRITAM
  • NALADADI GHRITAM
  • NIRURYADI GULIKA
  • PUNARNAVADI MANDURAM
  • VILWADI GULIKA
  • MAHATIKTAM KASHAYAM
  • VARAVISALADI KASHAYAM
  • Haridra
  • VASISHTHARASAYANAM

 

  • Interation of Guggulu (Commiphora mukul) and some modern medicines

 

It should be used with caution when combined with warfarin and other anticoagulants, as it has antiplatelet activity and can increase the clotting time.

It stimulates the thyroid gland and is especially useful where tri iodo thyronine (T3) levels are low. So it may alter the dosing requirements of thyroid medications.

Guggululipid an active principle of Commiphora mukul when co-administered with propanolol, an antihypertensive or diltiazem decreases the bioavailability of these drugs.

 

Ayurveda medicines which contains  Guggulu

 

 

  • Guggulupanchapalachurnam
  • Guggulutiktakaghritam
  • Guggulutiktakam kashayam
  • KËØCANËRA GUGGULU
  • KAIáORA GUGGULU
  • GOKâURËDI GUGGULU
  • TRAYODAáË×GA GUGGULU
  • TRIPHALË GUGGULU
  • MAHA YOGARËJA GUGGULU
  • YOGARËJA GUGGULU
  • LËKâË GUGGULU
  • VYOâËDI GUGGULU
  • VËTËRI GUGGULU
  • SAPTAVIMáATIKA GUGGULU
  • SIêHANËDA GUGGULU

 

  • Interation with Rasona (Allium sativum) and some modern medicines

Rasona interacts with anticoagulants like warfarin and NSAIDs by decreasing platelet aggregation activity and may lead to bleeding tendencies. It may also interact along with high doses of alpha tocopherol that is vitamin E. It is reported to change pharmacokinetic variables of paracetamol, decreases blood concentrations of warfarin and produces hypoglycaemia when taken with chlorpropamide.

 Rasona reduces the plasma level concentration of saquinavir, antiretroviral drug used in HIV therapy and can also interact with other protease inhibitors.

 

Ayurveda medicines which contains  Rasona (Allium sativum)

 

  • DHANADANAYANADI KASHAYAM
  • DHANADANAYANADI KASHAYAM
  • KULATHADI KASHAYAM
  • LASUNAIRANDADI KASHAYAM
  • PRASARANYADI KASHAYAM
  • HINGUTRIGUNALEHAM
  • HINGUTRIGUNATAILAM
  • NIRGUNDYADI GHRITAM
  • ANTRAKUTHARAM GULIKA
  • GOPICHANDANADI GULIKA
  • MUKKAMUKKATUVADI GULIKA
  • PATHADI GULIKA
  • PONKARADI GULIKA
  • SETUBANDHAM GULIKA

 

  • Interation with Aswagandha (Withania somnifera) and some modern medicines

It potentiate the effects of barbiturates and sedatives when used simultaneously. The drug has additive effect when used in combination with diazepam.

Ayurveda medicines which contains  Aswagandha (Withania somnifera)

 

  • ASWAGANDHACHURNAM
  • ASOKAGHRITAM
  • AJASWAGANDHADI LEHAM
  • ASWAGANDHARISHTAM
  • BALARISHTAM
  • DASAMULARISHTAM
  • DHANWANTARARISHTAM
  • MRITASANJIVANI ARISHTAM
  • SARASWATARISHTAM
  • SUDARSANASAVAM
  • AMRITAPRASAGHRITAM
  • ASOKAGHRITAM
  • BRIHACCHAGALADI GHRITAM
  • MAHAKALYANAKAGHRITAM
  • MAHATRAIPHALAGHRITAM
  • NIRGUNDYADI GHRITAM

 

  • Interation with Sunti (Zingiber officinale) and some modern medicines

 

Sunti can interact with anti-inflammatory medications such as ibuprofen. It can also interact with aspirin, warfarin, heparin and other drugs that effect bleeding tendencies or platelet count.

Most of the Ayurvedic kashaya contains Sunti (Zingiber officinale) as one of the ingredient , only a few with out shunti

  • Interation of Jatamamsi (Nardostachys jatamamsi)  and some modern medicines

Jatamamsi is to be given cautiously in patients on benzodiazepine or any other sedative medicine. It is also to be given with caution with anti hypertensive medicine as it may have additive effect.

Ayurveda medicines which contains Jatamamsi (Nardostachys jatamamsi)  

 

  • DASAMULARISHTAM
  • SRIKHANDASAVAM
  • SARVAMAYANTAKAGHRITAM
  • VASISHTHARASAYANAM

 

  • Drug interaction involving Yashtimadhu (Glycyrrhiza glabra)

 

Glycyrrhizin in Yashtimadhu decreases plasma clearance, and increases plasma concentration of prednisolone and thus its action is enhanced. It also causes hypertension, oedema and hypokalemia when simultaneously used with oral contraceptives. It is reported that oral contraceptive use may increase sensitivity to glycyrrhizin. Women are reportedly more sensitive than men to adverse effects of Yashtimadhu. It should not be administered for prolonged time with thiazide and loop diuretics because it increases potassium loss.

 

Ayurveda medicines which contains Yashtimadhu (Glycyrrhiza glabra)

 

  • MAHATRAIPHALAGHRITAM
  • SUKUMARAGHRITAM
  • AJASWAGANDHADI LEHAM

 

 

  • Drug interaction involving alcohol

 

Arishtas and asavas are major dosage forms used in Ayurveda. They contain varying range of alcohol content. Alcohol is known to interact with aspirin and NSAIDs and cause increased risk of gastric mucosal damage and gastric bleeding. Many medications cause an unpleasant hypersensitivity to alcohol called “disulfiram effect”. Examples of such medications are antibiotics like metronidazole and tinidazole, sulfonylureas like tolbutamide etc

Arista and asava

 

  • Drug interaction involving castor oil (Ricinus communis)

castor oil (Ricinus communis) reduces the efficacy of antiarrythmic drugs, diuretics, fat soluble vitamins and antihistamines

 

  • Drug interaction involving (Mucuna pruriens)

(Mucuna pruriens) may potentiate the action of anti parkinson‟s medicine

 

  • Drug interaction involving Tulsi (Ocimum sanctum)

 

Tulsi (Ocimum sanctum) has been reported as hepatotoxic in rats with glutathione depleted liver. So concurrent use with paracetamol which depletes glutathione may be harmful.

Neelithulasadi kashayam

 

  • Drug interaction involving Daruharidra (Berberis aristata)

berberine in Daruharidra (Berberis aristata) with hypolipidaemic drugs like statins

 

Ayurveda medicines which contains Daruharidra (Berberis aristata)

 

  • DEVADARVYARISHTAM
  • NIMBAHARIDRADI CHURNAM
  • KALYANAKAGHRITAM
  • MAHAKALYANAKAGHRITAM
  • MAHAKALYANAKAGHRITAM
  • NALADADI GHRITAM
  • PUNARNAVADI MANDURAM
  • VILWADI GULIKA
  • MAHATIKTAM KASHAYAM
  • MANJISHTHADI KWATHAM

 

Caution : don't stop any medicine with out proper advice from the doctor ( concerned system of medicine )

 

Reference

 

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